原创力文档genetic and computational identification of a conserved bacterial metabolic module遗传和计算守恒的细菌代谢模块的识别.pdfVIP
- 1、本文档共12页，可阅读全部内容。
- 2、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
- 3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 5、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 6、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 7、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 8、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
genetic and computational identification of a conserved bacterial metabolic module遗传和计算守恒的细菌代谢模块的识别
Genetic and Computational Identification of a Conserved
Bacterial Metabolic Module
1 2,3,4 3 3 1
Cara C. Boutte , Balaji S. Srinivasan , Jason A. Flannick , Antal F. Novak , Andrew T. Martens ,
3 5 1,6,7
Serafim Batzoglou , Patrick H. Viollier , Sean Crosson *
1 Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, Illinois, United States of America, 2 Department of Statistics, Stanford University,
Stanford, California, United States of America, 3 Department of Computer Science, Stanford University, Stanford, California, United States of America, 4 Stanford Genome
Technology Center, Stanford University, Palo Alto, California, United States of America, 5 Department of Molecular Biology and Microbiology, Case Western Reserve
University, Cleveland, Ohio, United States of America, 6 The Committee on Microbiology, University of Chicago, Chicago, Illinois, United States of America, 7 Graduate
Program in Biophysical Sciences, University of Chicago, Chicago, Illinois, United States of America
Abstract
We have experimentally and computationally defined a set of genes that form a conserved metabolic module in the a-
proteobacterium Caulobacter crescentus and used this module to illustrate a schema for the propagation of pathway-level
annotation across bacterial genera. Applying comprehensive forward and reverse genetic methods and genome-wide
transcriptional analysis, we (1) confirmed the presence of genes involved in catabolism of the abundant environmental
sugar myo-inositol, (2) defined an operon encoding an ABC-family myo-inositol transm
您可能关注的文档
- functional diversification of paralogous transcription factors via divergence in dna binding site motif and in expression功能多样化paralogous转录因子通过dna结合位点的主题和散度表达式.pdf
- functional dorsoventral symmetry in relation to lift-based swimming in the ocean sunfish mola mola功能性背腹侧的对称与lift-based游泳在海里翻车鱼翻车鲀.pdf
- functional coverage of the human genome by existing structures, structural genomics targets, and homology models人类基因组的功能覆盖现有的结构,结构基因组学的目标,和同源性模型.pdf
- functional diffusion tensor imaging measuring task-related fractional anisotropy changes in the human brain along white matter tracts功能性扩散张量成像测量任务相关分数各向异性的变化人类大脑白质束.pdf
- functional enhancers at the gene-poor 8q24 cancer-linked locus功能增强剂gene-poor 8抓起与癌症相关的轨迹.pdf
- functional electrical stimulation of intrinsic laryngeal muscles under varying loads in exercising horses功能性电刺激运动内在喉部肌肉在不同负载下的马.pdf
- functional equivalency inferred from “authoritative sources” in networks of homologous proteins从u201c权威u201d功能相等的同源蛋白质的网络.pdf
- functional evaluation of genetic and environmental regulators of p450 mrna levels功能评价的遗传和环境监管机构p450 mrna水平.pdf
- functional evaluation of plasmodium export signals in plasmodium berghei suggests multiple modes of protein export功能评价鼠疟原虫出口信号表明多个蛋白出口模式.pdf
- functional evolution of leptin of ochotona curzoniae in adaptive thermogenesis driven by cold environmental stress瘦素的功能进化ochotona curzoniae在适应性生热作用受寒冷的环境压力.pdf
文档评论（0）