older men who use computers have lower risk of dementia年纪大的人使用电脑患上痴呆的风险较低.pdfVIP

Older Men Who Use Computers Have Lower Risk of Dementia Osvaldo P. Almeida1,2,3*, Bu B. Yeap4,5, Helman Alfonso1,2, Graeme J. Hankey4,6, Leon Flicker2,4,7, Paul E. Norman8 1 School of Psychiatry Clinical Neurosciences, University of Western Australia, Perth, Western Australia, Australia, 2 Western Australian Centre for Health Ageing, Centre for Medical Research, University of Western Australia, Perth, Western Australia, Australia, 3 Department of Psychiatry, Royal Perth Hospital, Perth, Western Australia, Australia, 4 School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia, 5 Department of Endocrinology and Diabetes, Fremantle Hospital, Fremantle, Western Australia, Australia, 6 Department of Neurology, Royal Perth Hospital, Perth, Western Australia, Australia, 7 Department of Geriatric Medicine, Royal Perth Hospital, Perth, Western Australia, Australia, 8 School of Surgery, University of Western Australia, Perth, Western Australia, Australia Abstract Objective: To determine if older men who use computers have lower risk of developing dementia. Methods: Cohort study of 5506 community-dwelling men aged 69 to 87 years followed for up to 8.5 years. Use of computers measured as daily, weekly, less than weekly and never. Participants also reported their use of email, internet, word processors, games or other computer activities. The primary outcome was the incidence of ICD-10 diagnosis of dementia as recorded by the Western Australian Data Linkage System. Results: 1857/5506 (33.7%) men reported using computers and 347 (6.3%) received a diagnosis of dementia during an average follow up of 6.0 years (range: 6 months to 8.5 years). The hazard ratio (HR) of dementia was lower among computer users than non-users (HR = 0.62, 95%CI = 0.47–0.81, after adjustment for age, educationa