upper gastrointestinal endoscopy detection of synchronous multiple primary cancers in esophagus and stomach single center experience from china上消化道内窥镜检测同步多个主要癌症在食道和胃单一中心从中国经验.pdfVIP

Hindawi Publishing Corporation Gastroenterology Research and Practice Volume 2012, Article ID 432367, 4 pages doi:10.1155/2012/432367 Clinical Study Upper Gastrointestinal Endoscopy Detection of Synchronous Multiple Primary Cancers in Esophagus and Stomach: Single Center Experience from China Rui Wang,1 Mo-Jin Wang,2 Jin-Lin Yang,1 and Cheng-Wei Tang1 1 Department of Gastroenterology and Endoscopy Center, West China Hospital, Sichuan University, Chengdu 610041, China 2 Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, China Correspondence should be addressed to Jin-Lin Yang, mouse-577@163.com Received 17 November 2011; Revised 21 January 2012; Accepted 25 January 2012 Academic Editor: Sergio Morini Copyright © 2012 Rui Wang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The present study was undertaken to clarify the prevalence and clinicopathological features of synchronous multiple primary cancers (SMPCs) under upper gastrointestinal endoscopic examination. We enrolled 45,032 consecutive patients who underwent upper gastrointestinal endoscopic examination for digestive disease from January 2006 to December 2007 in our hospital and analyzed the clinicopathological features of SMPCs in esophagus and stomach. SMPCs are defined as two or over two different cancerous lesions developing in the same or other organs within 6 months. SMPCs were identified in 46 patients (0.1%). The gender ratio was 5.6 : 1 (male/female) and the mean age was 59.4 years. Synchronous esophageal and gastric cancers were the most frequent, being seen in 32 patients (0.07%). The most common histol