熄风康对大鼠脑缺血保护作用（Protective effect of Xifeng Kang on cerebral ischemia in rats）.doc

熄风康对大鼠脑缺血保护作用（Protective effect of Xifeng Kang on cerebral ischemia in rats） Protective effect of Xifeng Kang on cerebral ischemia in rats Update Date: 2011-01-23 Click: Yu Shuling, Wu Jibiao, Cao Xiaolan Abstract the cerebral ischemia model of right neck A ligation was made in rats, and the protective effect of anti wind Kang was observed. The results show that the Xifeng Kang can obviously reduce rat nerve cell edema, reduce the water content of brain tissue in rats with cerebral ischemia; increased tPA, reduce PAI; inhibit the production of VWF, reduce the RBC aggregation index, increase the activity of AT- III; has obvious protective effect on experimental cerebral ischemia in rats. It is suggested that Xifeng Kang can obviously prevent thrombosis and relieve cerebral ischemic injury. Keywords extinguish wind Kang; cerebral ischemia; tPA; PAI; vWF; AT- III; The, Protective, Effects, of, XFK, on, Cerebral, Ischimia, Rats Yu, Shuling, Wu, Jibiao, Cao, Xiaolan Shandong, Thoracic, Hospital, Jinan 250014 Abstract The protective effects of Xi Feng Kang (XFK) were studied in cerebral ischimia rats induced by ligaturing right common carotid artery. The results indicated that XFK could significantly reduce edema of brain tissue cells, enhance tPA and AT- activity decrease PAI, vWF III, and RBC aggregation index of cerebral ischimia rats, significantly protect the experimental cerebral ischimia rats. The study prompted that the drug has the function of preventing cerebral thromloosis and reducing the injury of cerebral ischimia. Key, words, Xi, Feng, Kang; Cerebral ischimia; tPA; AT-; PAI; vWF; III Xifeng Kang by leech, scorpion, earthworm, Rhizoma Chuanxiong, Astragalus and other traditional Chinese medicine composition, Yiqihuoxue Tongluo expectorant effect. As the experience of clinical application for the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, mainly used for the treatment of stroke. To explore the mechanism, we use Xiaoshuan oral