病理生理学-第十一章 细胞信号转导与疾病（Pathophysiology - Chapter eleventh cellular signal transduction and disease）.docVIP

病理生理学-第十一章 细胞信号转导与疾病（Pathophysiology - Chapter eleventh cellular signal transduction and disease） Binding of stimulating antibodies to thyrotropin receptor The E. blocking receptor is associated with the thyrotropin receptor 17. major signal transduction disorders in Hashimotos disease (chronic lymphocytic thyroiditis) are A. decreases thyroid stimulating hormone secretion Downregulation or desensitization of thyrotropin receptor by B. C.Gs content decreased Binding of D. stimulating antibodies to thyrotropin receptor E. blocking antibodies bind to thyrotropin receptors 18. the effect of cholera toxin on G protein is A. promotes the binding of Gs to receptors B. stimulates Gs production C. increased the GTP enzyme activity of Gs D. inhibits GTP enzyme activity of Gs E. inhibits the binding of Gi to receptors The signal transduction pathway of type 19.A hypoparathyroidism is A. decreased parathyroid synthesis B. decreased parathyroid hormone receptor C.Gs decrease D. adenylate cyclase decreased E.cAMP degradation accelerated 20. does not belong to the clinical manifestation of pseudo hypoparathyroidism? A. parathyroid hormone secretion normal or increased B. increased blood phosphorus C. urinary calcium increased D. increased blood calcium E. hereditary bone dystrophy 21. pituitary adenoma caused by the abnormal signal transduction of acromegaly A. has too much growth hormone releasing hormone B. decrease in somatostatin secretion Mutations in the C. encoding Gs enabled Gs to continue to activate Mutations in D. encoding Gi reduced Gi function The sensitivity of E. to growth hormone was higher in peripheral tissues 22. which of the following is not a factor that activates NF - KB? A.TNF B. virus C. oxidizer D.IL one 10 E. endotoxin 23., signal transduction abnormalities unrelated to type 2 diabetes are A. insulin secretion is inadequate B. decreased insulin receptor synthesis C. the high insulin in the blood reduces its receptor D. encodes a P13K mutation E. reduced