药理学21（Pharmacology 21）.docVIP

药理学21（Pharmacology 21） Lesson 21 Teaching methods: (Please tick tick) theory class discussion class - Experiment - - - other exercises Class arrangement: 2 hours Teaching topic (Teaching chapters and sections or topics): the twenty-fourth chapter Kangxin colic medicine Teaching aims and requirements (three levels of mastery, familiarity and understanding): 1. to master the mechanism of anti myocardial ischemia by nitrates, beta blockers and calcium channel blockers. 2. grasp the clinical use of various kinds of anti myocardial ischemia drugs. Teaching emphases and difficulties: 1.. The mechanism, clinical application, pharmacokinetics and main adverse reactions of nitric oxide esters in anti myocardial ischemia. The mechanism and clinical use of 2. beta blockers and its effects on the mechanism of synergistic effects with nitrates. The mechanism, characteristics and clinical application of 3. calcium channel blockers verapamil and diltiazem in anti myocardial ischemia. Mechanism and clinical application of 1. nitrates against myocardial ischemia. Mechanism of drug resistance in 2. nitrates. 3. principles of increased blood flow in ischemic areas by nitrates, calcium channel blockers, and beta blockers. The principle that 4. calcium channel blockers and beta blockers combine with nitrates to promote each other. Basic content of teaching Angina pectoris is a rapid and transient myocardial ischemia and anoxia syndrome caused by coronary insufficiency. The clinical manifestations of the sternum precordial posterior and paroxysmal cramps or pain, often radiate to the left upper limb. Angina pectoris is generally divided into the following 3 types: stability angina pectoris, mostly in physical activity, and its typical cause is fatigue or emotional excitement. Unstable angina, including initial onset, worsening type and spontaneous angina pectoris, can lead to myocardial infarction or sudden death, and can gradually recover into stable angina pectoris. Variant angina is c