非瓣膜病心房颤动的抗血栓栓塞治疗（Antithrombotic therapy for nonvalvular atrial fibrillation）.docVIP

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非瓣膜病心房颤动的抗血栓栓塞治疗（Antithrombotic therapy for nonvalvular atrial fibrillation）.doc

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非瓣膜病心房颤动的抗血栓栓塞治疗（Antithrombotic therapy for nonvalvular atrial fibrillation）

非瓣膜病心房颤动的抗血栓栓塞治疗（Antithrombotic therapy for nonvalvular atrial fibrillation） Antithrombotic therapy for nonvalvular atrial fibrillation 2010-09-07 Yu Mengyue Liu Han A randomized clinical trial of thromboembolism in non valvular atrial fibrillation The risk factors of non valvular ventricular fibrillation embolism are ischemic stroke history, hypertension, diabetes, advanced age (over 65 years old), [3], etc.. The incidence of thromboembolic complications in non valvular atrial fibrillation was 2.98% to 6.30% [2]. 1989 Copenhagen AF aspirin and anticoagulant group (Copenhagen atrial fibrillation aspirin and anticoagulation study, AFASAK) in 1007 patients with nonvalvular atrial fibrillation were randomly divided into 3 groups: warfarin group 335 cases, 336 cases in the aspirin group, 336 patients in the placebo group, INR in 2.8 ~ 4.2 between the test results found during the warfarin group; than in the placebo group the incidence of thromboembolism decreased 71%, aspirin group than in the placebo group the incidence of thromboembolism decreased 18% (P0.05). For the first time, a randomized clinical trial was conducted to confirm the important role of anticoagulants in the prevention of thromboembolism in nonvalvular heart diseases (4). Since Europe and the United States and 5 randomized clinical trials group of non valvular atrial fibrillation thrombus embolism, respectively is the Boston area AF group (Boston area anticoagulant therapy test Anticoagulation Trial for atrial fibrillation, BAATAF), the prevention of atrial fibrillation embolism (stroke prevention in group of atrial fibrillation I, SPAF I), Canada atrial fibrillation anticoagulant the test group (Canadian atrial fibrillation Anticoagulation Trial, CAFA), veterans of the prevention of atrial fibrillation embolism (Veterans Affairs stroke research group prevention in atrial fibrillation study, SPINAF), the European AF trial research group (European Atrial Fibrillation Trial Study Group, EAFTA), the test