Care of high-dose methotrexate for adults with acute lymphoblastic leukemia（照顾大剂量甲氨蝶呤为成人急性淋巴细胞白血病）.docVIP

Care of high-dose methotrexate for adults with acute lymphoblastic leukemia Large doses of methotrexate (HD-MTX), is the prevention and treatment of adult acute lymphoblastic leukemia, and extramedullary leukemia and systemic consolidation and effective measures to strengthen the treatment. Tetrahydrofolate (CF4 calcium rescue, but the HD-MTX is a metabolic anti-tumor drug toxicity, the course of treatment is often accompanied by varying degrees of toxicity, to ensure the successful completion of chemotherapy, nursing is the key. our department from October 2008 to December 2010, 20 cases of