Changes of bleomycin-induced pulmonary fibrosis in rats hydroxyproline and oxidative stress indicators（的变化bleomycin-induced肺纤维化大鼠羟脯氨酸和氧化应激指标）.docVIP

Changes of bleomycin-induced pulmonary fibrosis in rats hydroxyproline and oxidative stress indicators Author: Liu Rui, Li Chenggang, Liang Xin, sea Chunxu [Keywords] pulmonary fibrosis [Abstract] AIM: To discuss the changes of hydroxyproline and the role of oxidationantioxidation disequilibrium in pulmonary fibrosis induced by bleomycin (BLM) in rats. METHODS: A single dose BLM was intratracheally injected to induce pulmonary fibrosis in rats, so as to observe the changes of tissue hydroxyproline and oxidativestress markers during the process. The animals were killed on the 3rd, 7th,