a further look at quantitative trait loci affecting growth and fatness in a cross between meishan and large white pig populations进一步审视影响数量性状的增长和肥胖之间的交叉梅山和大白猪的人群.pdfVIP

a further look at quantitative trait loci affecting growth and fatness in a cross between meishan and large white pig populations进一步审视影响数量性状的增长和肥胖之间的交叉梅山和大白猪的人群.pdf

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a further look at quantitative trait loci affecting growth and fatness in a cross between meishan and large white pig populations进一步审视影响数量性状的增长和肥胖之间的交叉梅山和大白猪的人群

Genet. Sel. Evol. 34 (2002) 193–210 193 © INRA, EDP Sciences, 2002 DOI: 10.1051/gse:2002003 Original article A further look at quantitative trait loci affecting growth and fatness in a cross between Meishan and Large White pig populations Raquel QUINTANILLAa∗∗, Denis MILANb , a∗ Jean-Pierre BIDANEL a Station de génétique quantitative et appliquée, Institut national de la recherche agronomique, 78352 Jouy-en-Josas Cedex, France b Laboratoire de génétique cellulaire, Institut national de la recherche agronomique, 31326 Castanet Tolosan Cedex, France (Received 23 April 2001; accepted 15 October 2001) Abstract – A detailed quantitative trait locus (QTL) analysis of growth and fatness data from a three generation experimental cross between Large White (LW) and Meishan (MS) pig breeds was carried out to search for sex × QTL interactions, imprinting effects and multiple linked QTLs. A total of 530 F2 males and 573 F2 females issued from 6 F1 boars and 23 F1 sows were typed for a total of 137 markers covering the entire porcine genome. Nine growth traits and three backfat thickness measurements were analysed. All analyses were performed using line cross regression procedures. A QTL with sex-specific expression was revealed in the proximal region of chromosome 8, although some confusion between herd and sex effects could not be discarded. This previously undetected QTL affected male growth during the fattening period, with a favourable additive effect of the LW allele. The analyses also revealed the presence of two linked QTLs segregating on chromosome 1, affecting growth traits du

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