a genetic code alteration generates a proteome of high diversity in the human pathogen candida albicans遗传密码变更产生的蛋白质组高多样性的人类病原体白色念珠菌.pdfVIP

a genetic code alteration generates a proteome of high diversity in the human pathogen candida albicans遗传密码变更产生的蛋白质组高多样性的人类病原体白色念珠菌.pdf

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a genetic code alteration generates a proteome of high diversity in the human pathogen candida albicans遗传密码变更产生的蛋白质组高多样性的人类病原体白色念珠菌

Volume 8, Issue 10, Article R206et al.Gomes2007 Open Access Research A genetic code alteration generates a proteome of high diversity in the human pathogen Candida albicans * * * * Ana C Gomes , Isabel Miranda , Raquel M Silva , Gabriela R Moura , Benjamin Thomas† † * , Alexandre Akoulitchev and Manuel AS Santos Addresses: *CESAM Department of Biology, University of Aveiro, 3810-193 Aveiro, Portugal. †Central Proteomics Facility, Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK. Correspondence: Manuel AS Santos. Email: msantos@ua.pt Published: 4 October 2007 Received: 10 May 2007 Revised: 31 July 2007 Genome Biology 2007, 8:R206 (doi:10.1186/gb-2007-8-10-r206) Accepted: 4 October 2007 The electronic version of this article is the complete one and can be found online at /2007/8/10/R206 © 2007 Gomes et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. expands the proteome of this human pathogen exponentially./pGenetic code alteration inpAn unusual decoding of leucine CUG codonsCandida albicans as serine in itCandida albicans /itrevealed unanticipated codon ambiguity, which Abstract

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