a meta-analytic assessment of a thyroglobulin marker for marbling in beef cattle整合评估甲状腺球蛋白标记在牛肉大理石花纹.pdfVIP

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a meta-analytic assessment of a thyroglobulin marker for marbling in beef cattle整合评估甲状腺球蛋白标记在牛肉大理石花纹.pdf

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a meta-analytic assessment of a thyroglobulin marker for marbling in beef cattle整合评估甲状腺球蛋白标记在牛肉大理石花纹

Genet. Sel. Evol. 38 (2006) 479–494 479 c INRA, EDP Sciences, 2006 DOI: 10.1051/gse:2006016 Original article A meta-analytic assessment of a Thyroglobulin marker for marbling in beef cattle a ∗ b a Ian A. W , Gerhard M , Daniel L. B , Kerrie L. M a b  , D. Jay S. H a School of Mathematical Sciences, Queensland University of Technology, GPO Box 2434 Brisbane, QLD 4001, Australia b Genetic Solutions Pty. Ltd., 31 Dover St. Albion, QLD 4010, Australia (Received 27 September 2005; accepted 20 April 2006) Abstract – A meta-analysis was undertaken reporting on the association between a polymor- phism in the Thyroglobulin gene (TG5) and marbling in beef cattle. A Bayesian hierarchical model was adopted, with alternative representations assessed through sensitivity analysis. Based on the overall posterior means and posterior probabilities, there is substantial support for an ad- ditive association between the TG5 marker and marbling. The marker eﬀect was also assessed across various breed groups, with each group displaying a high probability of positive associ- ation between the T allele and marbling. The WinBUGS program code used to simulate the