a parametric study delineating irreversible electroporation from thermal damage based on a minimally invasive intracranial procedure从热损伤参数的一项研究描述不可逆电穿孔根据微创颅内手术.pdfVIP

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a parametric study delineating irreversible electroporation from thermal damage based on a minimally invasive intracranial procedure从热损伤参数的一项研究描述不可逆电穿孔根据微创颅内手术.pdf

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a parametric study delineating irreversible electroporation from thermal damage based on a minimally invasive intracranial procedure从热损伤参数的一项研究描述不可逆电穿孔根据微创颅内手术

A Parametric Study Delineating Irreversible Electroporation from Thermal Damage Based on a Minimally Invasive Intracranial Procedure Garcia et al. Garcia et al. BioMedical Engineering OnLine 2011, 10:34 /content/10/1/34 (30 April 2011) Garcia et al. BioMedical Engineering OnLine 2011, 10:34 /content/10/1/34 RESEARCH Open Access A Parametric Study Delineating Irreversible Electroporation from Thermal Damage Based on a Minimally Invasive Intracranial Procedure 1 2 1 3 1* Paulo A Garcia , John H Rossmeisl Jr , Robert E Neal II , Thomas L Ellis and Rafael V Davalos * Correspondence: davalos@ Abstract 1Bioelectromechanical Systems Laboratory, School of Biomedical Background: Irreversible electroporation (IRE) is a new minimally invasive technique Engineering and Sciences, Virginia Tech - Wake Forest University, to kill undesirable tissue in a non-thermal manner. In order to maximize the benefits Blacksburg, VA, USA from an IRE procedure, the pulse parameters and electrode configuration must be Full list of author information is optimized to achieve complete coverage of the targeted tissue while preventing available at the end of the article thermal damage due to excessive Joule heating. Methods: We developed numerical simulations of typical protocols based on a previously published computed tomographic (CT) guided in vivo procedure. These models were adapted to assess the effects of temperature, electroporation, pulse