a thematic analysis of factors influencing recruitment to maternal and perinatal trials影响招聘的主题分析孕产妇和围产期试验.pdfVIP

BMC Pregnancy and Childbirth BioMed Central Review Open Access A thematic analysis of factors influencing recruitment to maternal and perinatal trials Rebecca L Tooher*, Philippa F Middleton and Caroline A Crowther Address: Discipline of Obstetrics and Gynaecology, University of Adelaide, Adelaide, Australia Email: Rebecca L Tooher* - rebecca.tooher@.au; Philippa F Middleton - philippa.middleton@.au; Caroline A Crowther - caroline.crowther@.au * Corresponding author Published: 7 August 2008 Received: 20 July 2007 Accepted: 7 August 2008 BMC Pregnancy and Childbirth 2008, 8:36 doi:10.1186/1471-2393-8-36 This article is available from: /1471-2393/8/36 © 2008 Tooher et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Recruitment of eligible participants remains one of the biggest challenges to successful completion of randomised controlled trials (RCTs). Only one third of trials recruit on time, often requiring a lengthy extension to the recruitment period. We identified factors influencing recruitment success and potentially effective recruitment strategies. Methods: We searched MEDLINE and EMBASE from 1966 to December Week 2, 2006, the Cochrane Library Methodology Register