adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin脂联素,retinol-binding蛋白质4,瘦素在旷日持久的肺动脉起源的关键疾病.pdfVIP

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adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin脂联素,retinol-binding蛋白质4,瘦素在旷日持久的肺动脉起源的关键疾病.pdf

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adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin脂联素,retinol-binding蛋白质4,瘦素在旷日持久的肺动脉起源的关键疾病

Available online /content/13/4/R112 Vol 13 No 4 Open Access Research Adiponectin, retinol-binding protein 4, and leptin in protracted critical illness of pulmonary origin 1 1 2 2 3 Lies Langouche , Sarah Vander Perre , Jan Frystyk , Allan Flyvbjerg , Troels Krarup Hansen and Greet Van den Berghe1 1Department of Intensive Care Medicine, Katholieke Universiteit Leuven, Herestraat 49, 3000 Leuven, Belgium 2The Medical Research Laboratories, Clinical Institute, Aarhus University Hospital, Nørrebrogade 42-44, 8000 Aarhus, Denmark 3Immunoendocrine Research Unit, Medicial Department M, Aarhus University Hospital, Norrebrogade 42-44, 8000 Aarhus, Denmark Corresponding author: Greet Van den Berghe, greet.vandenberghe@med.kuleuven.be Received: 6 Mar 2009 Revisions requested: 17 Apr 2009 Revisions received: 5 May 2009 Accepted: 9 Jul 2009 Published: 9 Jul 2009 Critical Care 2009, 13:R112 (doi:10.1186/cc7956) This article is online at: /content/13/4/R112 © 2009 Langouche et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited. Abstract Introduction Critically ill patients requiring intensive care Results During acute critical illness, circulating levels of uniformly develop insulin resistance. This is most pronounced in adiponectin, RBP4, and leptin were low. Patients with sepsis patients with sepsis. Recentl