administration of antibiotics via the respiratory tract for the prevention of icu-acquired pneumonia a meta-analysis of comparative trials政府通过呼吸道的抗生素预防icu-acquired肺炎比较试验的荟萃分析.pdfVIP
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administration of antibiotics via the respiratory tract for the prevention of icu-acquired pneumonia a meta-analysis of comparative trials政府通过呼吸道的抗生素预防icu-acquired肺炎比较试验的荟萃分析
Available online /content/10/4/R123
Vol 10 No 4 Open Access
Research
Administration of antibiotics via the respiratory tract for the
prevention of ICU-acquired pneumonia: a meta-analysis of
comparative trials
1,2,3 1 1 4
Matthew E Falagas , Ilias I Siempos , Ioannis A Bliziotis and Argyris Michalopoulos
1Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece
2Department of Medicine, Henry Dunant Hospital, Athens, Greece
3Department of Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA
4Intensive Care Unit, Henry Dunant Hospital, Athens, Greece
Corresponding author: Matthew E Falagas, m.falagas@aibs.gr
Received: 19 May 2006 Revisions requested: 12 Jul 2006 Revisions received: 19 Aug 2006 Accepted: 25 Aug 2006 Published: 25 Aug 2006
Critical Care 2006, 10:R123 (doi:10.1186/cc5032)
This article is online at: /content/10/4/R123
© 2006 Falagas et al.; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction The administration of prophylactic antibiotics via difference in mortality was found between the compared groups
the respiratory tract is one of several strategies for the (OR = 0.86, 95% CI 0.55–1.32). Data were too limited to
prevention of intensive care unit (ICU)-acquired pneumonia. We permit an analysis of colon
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