原创力文档antipsychotic medications and cognitive functioning in bipolar disorder moderating effects of comt val108158 met genotype抗精神病药物和认知功能在双相情感障碍缓和comt val108158遇到了基因型的影响.pdfVIP
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antipsychotic medications and cognitive functioning in bipolar disorder moderating effects of comt val108158 met genotype抗精神病药物和认知功能在双相情感障碍缓和comt val108158遇到了基因型的影响
Arts et al. BMC Psychiatry 2013, 13:63
/1471-244X/13/63
RESEARCH ARTICLE Open Access
Antipsychotic medications and cognitive
functioning in bipolar disorder: moderating
effects of COMT Val108/158 Met genotype
Baer Arts1*, Claudia JP Simons1,2, Marjan Drukker1 and Jim van Os1,3
Abstract
Background: There is a negative association between the use of antipsychotics and cognitive functioning in
bipolar patients, which may be mediated by altered dopamine signaling in selected bra
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