corticosteroids for severe sepsis an evidence-based guide for physicians糖皮质激素对严重脓毒症医师的循证指南.pdfVIP

Annane Annals of Intensive Care 2011, 1:7 /content/1/1/7 REVIEW Open Access Corticosteroids for severe sepsis: an evidence- based guide for physicians Djillali Annane Abstract Septic shock is characterized by uncontrolled systemic inflammation that contributes to the progression of organ failures and eventually death. There is now ample evidence that the inability of the host to mount an appropriate hypothalamic-pituitary and adrenal axis response plays a major in