egfr inhibition in non-small cell lung cancer current evidence and future directions在非小细胞肺癌表皮生长因子受体抑制当前证据和未来的方向.pdfVIP

Chi et al. Biomarker Research 2013, 1:2 /content/1/1/2 REVIEW Open Access EGFR inhibition in non-small cell lung cancer: current evidence and future directions Alexander Chi1*, Scot Remick2 and William Tse3 Abstract EGFR inhibition has emerged to be an important strategy in the treatment of non-small cell lung cancer (NSCLC). Small molecule tyrosine kinase inhibitors (TKIs) and mono-clonal antibodies (mAbs) to the EGFR have been tested in multiple large randomiz