a point mutation in the hair cell nicotinic cholinergic receptor prolongs cochlear inhibition and enhances noise protection头发的点突变细胞烟碱胆碱能受体延长耳蜗抑制和增强噪音保护.pdfVIP
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a point mutation in the hair cell nicotinic cholinergic receptor prolongs cochlear inhibition and enhances noise protection头发的点突变细胞烟碱胆碱能受体延长耳蜗抑制和增强噪音保护
PLoS BIOLOGY
A Point Mutation in the Hair Cell Nicotinic
Cholinergic Receptor Prolongs Cochlear
Inhibition and Enhances Noise Protection
1,2 ´ 3 1 1 1 2
Julian Taranda , Stephane F. Maison , Jimena A. Ballestero , Eleonora Katz , Jessica Savino , Douglas E. Vetter ,
Jim Boulter4 3 5 ´ 1,6*
, M. Charles Liberman , Paul A. Fuchs , A. Belen Elgoyhen
´ ´ ´ ´ ´
1 Instituto de Investigaciones en Ingenierıa Genetica y Biologıa Molecular, Consejo Nacional de Investigaciones Cientıficas y Tecnicas, Buenos Aires, Argentina, 2 Department
of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts, United States of America, 3 Department of Otology and Laryngology, Harvard Medical School
and Eaton–Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States of America, 4 Department of Psychiatry and Biobehavioral
Sciences, Hatos Research Center for Neuropharmacology, Brain Research and Molecular Biology Institutes, University of California, Los Angeles, United States of America,
5 Department of Otolaryngology, Head and Neck Surgery, and Center for Hearing and Balance, The Johns Hopkins University School of Medicine, Baltimore, Maryland,
´
United States of America, 6 Departamento de Farmacologıa, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina
The transduction of sound in the auditory periphery,
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