apoptosis signaling is altered in cd4+cd25+foxp3+ t regulatory lymphocytes in pre-eclampsia细胞凋亡信号改变监管淋巴细胞cd4 + cd25 + foxp3 + t在先兆子痫.pdfVIP
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apoptosissignalingisalteredincd4cd25foxp3tregulatorylymphocytesinpre-eclampsia细胞凋亡信号改变监管淋巴细胞cd4cd25foxp3t在先兆子痫
Int. J. Mol. Sci. 2012, 13, 6548-6560; doi:10.3390/ijm
OPEN ACCESS
International Journal of
Molecular Sciences
ISSN 1422-0067
/journal/ijms
Article
+ + +
Apoptosis Signaling Is Altered in CD4 CD25 FoxP3 T
Regulatory Lymphocytes in Pre-Eclampsia
Dorota Darmochwal-Kolarz 1,*, Shigeru Saito 2, Jacek Tabarkiewicz 3, Bogdan Kolarz 3,
3 1 1
Jacek Rolinski , Bozena Leszczynska-Gorzelak and Jan Oleszczuk
1 Department of Obstetrics and Perinatology, Medical University of Lublin,
Lublin 20-950, Al. Raclawickie 1, Poland; E-Mails: b.leszczynska@umlub.pl (B.L.-G.);
jan.oleszczuk@umlub.pl (J.O.)
2 Department of Obstetrics and Gynecology, University of Toyama, 2630 Sugitani, Toyama
930-0194, Japan; E-Mail: s30saito@med.u-toyama.ac.jp
3 Department of Clinical Immunology, Medical University of Lublin, Lublin 20-950,
Al. Raclawickie 1, Poland; E-Mails: kolgen@wp.pl (J.T.); bogdank@mp.pl (B.K.);
jacek.rolinski@ (J.R.)
* Author to whom correspondence should be addressed; E-Mail: dorotak@mp.pl;
Tel.: +48-81-7244-769; Fax: +48-81-7244-841.
Received: 17 April 2012; in revised form: 21 May 2012 / Accepted: 22 May 2012 /
Published: 29 May 2012
Abstract: The aim of our study was to estimate the surface expressions of CD95
(APO-1/Fas) antigen and the intracellular expres
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