原创力文档regional homogeneity within the default mode network in bipolar depression a resting-state functional magnetic resonance imaging study地区在默认模式网络同质性双相抑郁静息状态功能磁共振成像研究.pdfVIP
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regional homogeneity within the default mode network in bipolar depression a resting-state functional magnetic resonance imaging study地区在默认模式网络同质性双相抑郁静息状态功能磁共振成像研究
Regional Homogeneity within the Default Mode Network
in Bipolar Depression: A Resting-State Functional
Magnetic Resonance Imaging Study
1,2 2,3 2 2 2 4 4
Chun-Hong Liu , Xin Ma , Feng Li , Yong-Jun Wang , Chang-Le Tie , Su-Fang Li , Tao-Lin Chen , Ting-
5 1 1 4,5 4,5 2,6,7
ting Fan , Yu Zhang , Jie Dong , Li Yao , Xia Wu *, Chuan-Yue Wang *
1 Department of Radiology, Beijing Anding Hospital, Capital Medical University, Beijing, China, 2 Beijing Key Lab of Mental Disorders, Beijing Anding Hospital, Capital
Medical University, Beijing, China, 3 Center of the Treatment in Depressive Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China, 4 State Key
Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing, China, 5 College of Information Science and Technology, Beijing Normal University,
Beijing, China, 6 Beijing Key Laboratory of Brain Major Disorders - State Key Lab Incubation Base, Capital Medical University, Beijing, China, 7 Beijing Neuroscience
Disciplines, Capital Medical University, Beijing, China
Abstract
Aim: We sought to use a regional homogeneity (ReHo) approach as an index in resting-state functional magnetic resonance
imaging (fMRI) to investigate the features of spontaneous brain activity within the default mode network (DMN) in patients
suffering from bipolar depression (BD).
Methods: Twenty-six patients with BD and 26 gender-, age-, and education-matched healthy subjects participated in the
resting-state fMRI scans. We compared the differences in ReHo between the two groups within the DMN and investigate
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