regular exercise is associated with a reduction in the risk of nafld and decreased liver enzymes in individuals with nafld independent of obesity in korean adults定期锻炼是与非酒精性脂肪肝的风险减少和降低肝酶在非酒精性脂肪肝患者独立于韩国成年人的肥胖.pdfVIP

Regular Exercise Is Associated with a Reduction in the Risk of NAFLD and Decreased Liver Enzymes in Individuals with NAFLD Independent of Obesity in Korean Adults 1. 1. 2 2 2 2 Ji Cheol Bae , Sunghwan Suh , Se Eun Park , Eun Jung Rhee , Cheol Young Park , Ki Won Oh , Sung 2 2 1 1 1 1 Woo Park , Sun Woo Kim , Kyu Yeon Hur , Jae Hyeon Kim , Myung-Shik Lee , Moon Kyu Lee , Kwang- 1 2 Won Kim , Won-Young Lee * 1 Division of Endocrinology and Metabolism, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea, 2 Division of Endocrinology and Metabolism, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea Abstract Background: We evaluated the association of regular physical exercise with the presence of non-alcoholic fatty liver disease (NAFLD) and liver enzymes in relation to obesity and insulin resistance. Methodology/Principal Findings: A cross-sectional analysis was conducted in 72,359 healthy Korean adults without diabetes who participated in a comprehensive health check-up. Subjects who have been exercising regularly (more than 3 times per week, at least for 30 minutes each time and for consecutive 3 month) were categorized into exercise group. All subjects were categorized into deciles based on their body mass index (BMI) and we estimated the odds ratios (ORs) for having NAFLD according to exercise regularity in each decile. The diagnosis of NAFLD was based on ultrasonography findings