serum 25(oh)d is a 2-year predictor of all-cause mortality, cardiac death and sudden cardiac death in chest pain patients from northern argentina血清25(oh)d是一个2年的全因死亡率的预测,心脏死亡和心脏性猝死在胸痛病人从阿根廷北部.pdfVIP
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serum 25(oh)d is a 2-year predictor of all-cause mortality, cardiac death and sudden cardiac death in chest pain patients from northern argentina血清25(oh)d是一个2年的全因死亡率的预测,心脏死亡和心脏性猝死在胸痛病人从阿根廷北部
Serum 25(OH)D Is a 2-Year Predictor of All-Cause
Mortality, Cardiac Death and Sudden Cardiac Death in
Chest Pain Patients from Northern Argentina
1,2 ´ 1,2,3 4 1
Patrycja A. Naesgaard *, Ricardo A. Leon De La Fuente , Stein Tore Nilsen , Leik Woie ,
4 5 6 1
Torbjoern Aarsland , Cato Brede , Harry Staines , Dennis W. T. Nilsen
1 Department of Cardiology, Stavanger University Hospital, Stavanger, Norway, 2 Institute of Medicine, University of Bergen, Bergen, Norway, 3 Cardiology Research
Institute, Catholic University of Salta, Salta, Argentina, 4 Department of Research, Stavanger University Hospital, Stavanger, Norway, 5 Department of Medical
Biochemistry, Stavanger University Hospital, Stavanger, Norway, 6 Sigma Statistical Services, Balmullo, United Kingdom
Abstract
Background: Several studies have shown an association between vitamin D deficiency and cardiovascular risk. Vitamin D
status is assessed by determination of 25-hydroxyvitamin D [25(OH)D] in serum.
Methods: We assessed the prognostic utility of 25(OH)D in 982 chest-pain patients with suspected acute coronary
syndrome (ACS) from Salta, Northern Argentina. 2-year follow-up data including all-cause mortality, cardiac death and
sudden cardiac death were analyzed in quartiles of 25(OH)D, applying univariate and multivariate analysis.
Results: There were statistically significant changes in seasonal 25(OH)D levels. At follow-up, 119 patients had died. The
mean 25(OH)D levels were significantly lower among patients dying than in long-term survivors, both in the total
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