simple ways to measure behavioral responses of drosophila to stimuli and use of these methods to characterize a novel mutant简单的方法来衡量果蝇的行为反应的刺激和使用这些方法来描述一种新的突变.pdfVIP

Simple Ways to Measure Behavioral Responses of Drosophila to Stimuli and Use of These Methods to Characterize a Novel Mutant 1 1,2 1 Lar L. Vang , Alexei V. Medvedev , Julius Adler * 1 Departments of Biochemistry and Genetics, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, 2 Department of Microbiology and Immunology, Georgetown University, Georgetown, Washington, D.C., United States of America Abstract The behavioral responses of adult Drosophila fruit flies to a variety of sensory stimuli – light, volatile and non-volatile chemicals, temperature, humidity, gravity, and sound - have been measured by others previously. Some of those assays are rather complex; a review of them is presented in the Discussion. Our objective here has been to find out how to measure the behavior of adult Drosophila fruit flies by methods that are inexpensive and easy to carry out. These new assays have now been used here to characterize a novel mutant that fails to be attracted or repelled by a variety of sensory stimuli even though it is motile. Citation: Vang LL, Medvedev AV, Adler J (2012) Simple Ways to Measure Behavioral Responses of Drosophila to Stimuli and Use of These Methods to Characterize a Novel Mutant. PLoS ONE 7(5): e37495. doi:10.1371/journal.pone.0037495 Editor: Aravinthan Samuel, Harvard University, United States of America Received November 8, 2011; Accepted April 19, 2012; Published May 23, 2012 Copyright: 2012 Vang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Funding: The authors have no funding or support to repor