telomere recombination accelerates cellular aging in saccharomyces cerevisiae端粒在酿酒酵母重组加速细胞老化.pdfVIP

Telomere Recombination Accelerates Cellular Aging in Saccharomyces cerevisiae Xiao-Fen Chen, Fei-Long Meng, Jin-Qiu Zhou* The State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Graduate School of the Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, People’s Republic of China Abstract Telomeres are nucleoprotein structures located at the linear ends of eukaryotic chromosomes. Telomere integrity is required for cell proliferation and survival. Although the vast majority of e