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各肿瘤标志物异常结果分析(Analysis of abnormal results of tumor markers)
各肿瘤标志物异常结果分析(Analysis of abnormal results of tumor markers)
Analysis of abnormal indicators of tumor markers
More related articles time: 2009-3-31 13:20:05, click: 441
Alpha fetoprotein (AFP) normal: Adults 0 ~ 25 mu g/L; infants (3 weeks -6 months) 0 ~ 39 g/L.
Methods: venous blood 2ml, no anticoagulation, and serum isolation were determined.
Abnormal condition:
1. in patients with primary hepatocellular carcinoma serum AFP increased significantly, about 77.1% of patients AFP500 mu g/L, but there are 18% patients without AFP elevation, it is worth noting.
2. in patients with viral hepatitis and cirrhosis, AFP has increased to varying degrees, but its level is often 300 g/L, in fact, most patients are 100 mu g/L. The reason for the elevation of AFP is mainly due to the regeneration of damaged hepatocytes. When immature, the liver cells re produce the ability to produce AFP, and with the repair of damaged hepatocytes, AFP gradually returned to normal.
3. serum levels of AFP were increased in patients with embryonal carcinoma of the gonads. 4. months after the onset of pregnancy, serum AFP levels began to rise, reaching a peak at 7~8 months, usually at 400 g/L
Cancer antigen 50 (CA50) normal: 0 ~ 23 kU/L
CA50 and CA19-9 have some cross antigenicity, which are mainly used in the diagnosis and monitoring of pancreatic cancer, colorectal cancer, and gastric cancer.
Abnormal condition:
1. pancreatic cancer, colon cancer, rectal cancer, gastric cancer and other gastrointestinal malignant tumors, serum cA50 increased, especially in patients with pancreatic cancer is the most obvious increase.
2., liver cancer, lung cancer, uterine cancer, ovarian cancer, renal cancer, breast cancer and so on can also be seen elevated cA50, so CA50 is a non-specific broad spectrum tumor markers.
3., ulcerative colitis, cirrhosis, melanoma, lymphoma, autoimmune diseases, such as elevated CA50 phenomenon.
Squamous cell carcinoma antigen (SCC) normal: 0 ~ 1.5 ng/ml
SCC is a specific tumor marke
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