倍他司汀（Duloxetine）.docVIP

倍他司汀（Duloxetine） [name of drug] Chinese Name: duloxetine English Name: Betahistine Other names: 100 sistin, betahistine mesylate betahistine, microser, sensitive and sensitive to Lang Lang, he, Pei amine, betahistine, Ruimeilier, Thailand, microser xiqiding, betahistine hydrochloride, Batahistine, Betahistine, betahistine hydrochloride Hydrochloride, Betahistine Mesilate, Betahistine Mesylate, Betahistinum, Betaserc, Merislon, Microser, Serc, Vasomotal. [clinical application] The 1. is mainly used for the treatment of Menieres disease (inner ear vertigo). 2., for acute cerebrovascular diseases (such as transient ischemic attack, cerebral embolism, etc.) and the central vertigo caused by it, can also be used for cerebral arteriosclerosis, headache caused by a variety of reasons (such as vascular headache). 3. for head trauma or hypertension caused by postural vertigo, tinnitus and so on. 4. for the treatment of bedsore, can promote wound healing. [pharmacology] 1. 、 pharmacodynamics is a new type of histamine. Its chemical structure and pharmacological properties are similar to that of histamine. It is a weak agonist of histamine H1 receptor and a strong antagonist of H3 receptor. It has almost no effect on H2 receptor. This drug can selectively act on H1 receptor, with the expansion of capillaries, relaxation of precapillary sphincter, increase of capillary blood flow, also can reduce the inner ear venous pressure, promote inner ear lymph absorption and increase blood flow of inner ear. The drug can also suppress the negative feedback regulation of histamine release by inhibiting the H3 receptor. This medicine to improve microcirculation and can also increase the stability of the inner hair cells, reduce the vestibular nerve conduction, enhance vestibular organ compensatory function, reduce the hydrolabyrinth, thereby eliminating the inner ear vertigo, tinnitus and ear sensation and other symptoms. The vasodilator action of this medicine is weaker and longer than hi