基于依诺沙星的不良反应（The adverse reaction of enoxacin based on）.docVIP

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基于依诺沙星的不良反应（The adverse reaction of enoxacin based on）.doc

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基于依诺沙星的不良反应（The adverse reaction of enoxacin based on）

基于依诺沙星的不良反应（The adverse reaction of enoxacin based on） The adverse reaction of enoxacin based on Date: 05, 25 Abstract: enoxacin; adverse reaction; clinical symptoms Enoxacin is the third generation of quinolone antibiotics, fungicides, A subunit by functions in bacterial DNA gyrase, synthesis and inhibition of DNA replication and leads to the death of bacteria, the antibacterial spectrum, especially for aerobic gram-negative bacilli with high antimicrobial activity, Neisseria, disease resistant to penicillin enzyme producing Haemophilus influenzae Mora and the bacteria were highly antibacterial activity, with good anti microbial functions of Chlamydia trachomatis, mycoplasma, Legionella, of Mycobacterium tuberculosis and atypical mycobacteria have antibacterial activity. Therefore, enoxacin preparation is widely used now in clinic, the adverse reactions also occur, this paper summarizes the relevant reports in recent years, for clinical reference. 1 allergic reactions Gao Jinjuan 1 reported cases, 1 patients, female, 24 years old, diagnosed as bronchitis, to Enoxacin Gluconate Injection 0.2 g/100 ml intravenous infusion of 5 min patients after feeling heart palpitations, chest tightness, wound pain, since a needle up to 20 cm upstream thrombophlebitis, arm skin see red rash. Immediately after discontinuation of the drug, about 30 min, the patient had no chest tightness, palpitation, symptomatic relief, and thrombophlebitis gradually disappeared. 2 cases of patients, female, 26 years old, a clinical diagnosis of tonsillitis, treated with penicillin G sodium (skin test negative) 4 million 800 thousand U+5% glucose 5 00ml, 1 /d and 0.2 g/100, Enoxacin Gluconate Injection ml, /d 1. After the intravenous drip to penicillin, Enoxacin Gluconate Injection 50 ml, patients feel palpitations, chest tightness, wound pain, since a needle up to 20 cm upstream thrombophlebitis, arm skin see red rash. Immediate discontinuation of the drug, approximately 30 min, relieved the patien