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Abstract
Ab
stract
objeetives:
To theeffect stress theformationofatherosclerosis
of eventson
explore spirit
andits
drugprevention.
Methods:
Establishatherosclerosismodel inrabbitswith food
byfeeding hi曲一cholesterol
dividedthem3 intervention
and intogroups,simvastatin group,n
randomly group(E
=1 ferulateintervention
2),sodium group(Fgroup,n=12),non-interventiongroup
thesame withoutstresscontrol
time,establish
(Ggroup,n=12),at hi曲·cholesterol
without controls 2
group(Dgroup,n=10),stress higll-cholesterolgroup(Hgroup,n
1 blankcontrol rabbitsin andH
0)and group(Igroup,n=6).StimulategroupE,F,G
buildstress for7 bloodofallanimalson 7andin
model,timedays.Draw day1,day
week1 inbloodwithELISA 13
ET-1,NE,hsCRP,IL-6 weeks,
3m.Assay assay.After
oftheaortathe
killalltheanimals.Selectthe of animal,oilred’’0”staining
part
the withcameraand theareaof
captureimage analysis plaqueusingcomputerimage
about3mmofthe sectionsineach to
aorta,HE
software.Intercept staining group
observe and formation.
morphologyplaque
Results
1.Bloodindicators:
andIL一6levels
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