新西兰兔左室心外膜下心肌坏死时头胸导联及常规导联心电图Q波比.doc

新西兰兔左室心外膜下心肌坏死时头胸导联及常规导联心电图Q波比 　【关键词】 常规导联；头胸导联；心电图；心肌疾病；参比点 　　Comparison of ECGs of New Zealand rabbits with myocardial necrosis recorded by headchest leads and routine leads 　　【Abstract】 AIM: To observe and compare the ECGs of the New Zealand rabbits with normal myocardium or myocardial necrosis recorded by headchest lead and routine leads, and to summarize their changes and explore their mechanisms. METHODS: A selfmade doublebarreled cannula was used to attach on the anterior wall of left ventricle. Some pure icecold acetic acid was poured on the anterior wall to induce a regional necrosis. An ECG instrument in whole synchronization of 24 leads was used to record the ECGs of the rabbits with normal or myocardial necrosis and analyze the wave shape and swing of the 2 different kinds of ECGs. RESULTS: The most of left ventricular myocardial necrosis were subepicardial necrosis which was limited in the half of the ventricular wall. The numbers of leads and rabbits with necrosis wave Q recorded by headchest leads were less than those recorded by routine leads. CONCLUSION: In the left ventricular subepicardial necrosis, the number of necrosis wave Q recorded by headchest leads is less than that recorded by routine leads. The former is consistent with pathological examination. Headchest leads indicate a more limited necrosis region. 　　【Keywords】 routine lead; head chest lead; electrocardiogram; cardiomyopathies; reference point 　　【摘要】 目的：用头胸导联和常规导联对比观察新西兰兔正常、心肌坏死状态下心电图变化的差异. 总结变化规律. 探讨其形成的机制. 方法：用自制的双层套管吸附在兔左心室前壁的表面. 注入纯冰醋酸造成局部的心肌坏死. 心电图仪同步记录新西兰兔正常状态、心肌坏死状态下头胸导联和常规导联心电图. 对二种心电图的波形、振幅进行比较. 结果：左室心外膜下心肌坏死时，坏死未贯通心室壁的1/2. 左胸头胸导联有坏死性Q波的新西兰兔例数及导联数明显少于常规导联. 结论：在新西兰兔左室心外膜下心肌坏死时，头胸导联坏死性Q波数量明显少于常规导联. 反映心肌坏死更加集中，与病理检查更符合. 　　【关键词】 常规导联；头胸导联；心电图；心肌疾病；参比点 　　0引言 　　心电图创立已有100周年. 为心血管疾病的诊断治疗做出了巨大的贡献. 但在长期的应用中人们也发现其存在的许多缺点. 多年来人们进行了不断的研究，试图解决这些问题. 头胸导联是我国学者独创的一种心电图［1］. 已有许多实验发现在人体表心电图中其P、R波幅大于常规导联，在正常人体中异常Q波明显少于常规导联. 有利于临床心电图的分析. 本实验试图用同步对比的方法对其与常规心电图的Q波进行比较. 探讨其在心肌坏死中的诊断价值. 　　1对象和方法 　　1