a single immunization with ha dna vaccine by electroporation induces early protection against h5n1 avian influenza virus challenge in mice单个免疫与ha dna疫苗通过电穿孔诱发小鼠早期预防h5n1型禽流感病毒的挑战.pdfVIP

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a single immunization with ha dna vaccine by electroporation induces early protection against h5n1 avian influenza virus challenge in mice单个免疫与ha dna疫苗通过电穿孔诱发小鼠早期预防h5n1型禽流感病毒的挑战.pdf

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a single immunization with ha dna vaccine by electroporation induces early protection against h5n1 avian influenza virus challenge in mice单个免疫与ha dna疫苗通过电穿孔诱发小鼠早期预防h5n1型禽流感病毒的挑战

BMC Infectious Diseases BioMed Central Research article Open Access A single immunization with HA DNA vaccine by electroporation induces early protection against H5N1 avian influenza virus challenge in mice 1,2 3 4 1 Liyun Zheng , Fuyan Wang , Zhongdong Yang , Jianjun Chen , 3 1,3,4 Haiyan Chang and Ze Chen* Address: 1State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, PR China, 2Graduate University of Chinese Academy of Sciences, Beijing 100049, PR China, 3College of Life Science, Hunan Normal University, Changsha 410081, Hunan, PR China and 4Shanghai Institute of Biological Products, Shanghai 200052, PR China Email: Liyun Zheng - zlyfxz981@126.com; Fuyan Wang - wfy0410@; Zhongdong Yang - zdyang@; Jianjun Chen - chenjj126@126.com; Haiyan Chang - changhaiyan@; Ze Chen* - chenze2005@263.net * Corresponding author Published: 12 February 2009 Received: 30 May 2008 Accepted: 12 February 2009 BMC Infectious Diseases 2009, 9:17 doi:10.1186/1471-2334-9-17 This article is available from: /1471-2334/9/17 © 2009 Zheng et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Developing vaccines for the preve