a smac-mimetic sensitizes prostate cancer cells to trail-induced apoptosis via modulating both iaps and nf-kappab一个smac-mimetic糖分会让前列腺癌的细胞通过调节iap和nf-kappab trail-induced细胞凋亡.pdfVIP

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a smac-mimetic sensitizes prostate cancer cells to trail-induced apoptosis via modulating both iaps and nf-kappab一个smac-mimetic糖分会让前列腺癌的细胞通过调节iap和nf-kappab trail-induced细胞凋亡.pdf

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a smac-mimetic sensitizes prostate cancer cells to trail-induced apoptosis via modulating both iaps and nf-kappab一个smac-mimetic糖分会让前列腺癌的细胞通过调节iap和nf-kappab trail-induced细胞凋亡

BMC Cancer BioMed Central Research article Open Access A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB †1,4 †2 1 1 1 Yao Dai , Meilan Liu , Wenhua Tang , Yongming Li , Jiqin Lian , Theodore S Lawrence 1,3 and Liang Xu*1,3 Address: 1Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA, 2Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA, 3Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA and 4Current address : Department of Radiation Oncology, University of Florida Health Science Center, Gainesville, FL 32610 Email: Yao Dai - daiyao@; Meilan Liu - lmiu@; Wenhua Tang - wenhuat@; Yongming Li - yongmli@; Jiqin Lian - lianj@; Theodore S Lawrence - tsl@; Liang Xu* - liangxu@ * Corresponding author †Equal contributors Published: 6 November 2009 Received: 30 October 2008 Accepted: 6 November 2009 BMC Cancer 2009, 9:392 doi:10.1186/1471-2407-9-392 This article is available from: /1471-2407/9/392 © 2009 Dai et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Although tumor necrosis factor-related apoptosis-inducing ligand