a structure filter for the eukaryotic linear motif resource真核生物线性结构滤波器的主题资源.pdfVIP

BMC Bioinformatics BioMed Central Methodology article Open Access A structure filter for the Eukaryotic Linear Motif Resource 1,4 2 3 2 Allegra Via* , Cathryn M Gould , Christine Gemünd , Toby J Gibson* and Manuela Helmer-Citterich1 Address: 1Center for Molecular Bioinformatics, Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, Rome, Italy, 2European Molecular Biology Laboratory, Postfach 10.2209, 69012 Heidelberg, Germany, 3Cellzome AG, Heidelberg, Germany and 4Current address: Biocomputing group, Department of Biochemical Science, Sapienza University of Rome, P.le Aldo Moro 5, Rome, Italy Email: Allegra Via* - allegra.via@uniroma1.it; Cathryn M Gould - gould@embl.de; Christine Gemünd - Christine.Gemuend@; Toby J Gibson* - gibson@embl.de; Manuela Helmer-Citterich - citterich@uniroma2.it * Corresponding authors Published: 24 October 2009 Received: 23 December 2008 Accepted: 24 October 2009 BMC Bioinformatics 2009, 10:351 doi:10.1186/1471-2105-10-351 This article is available from: /1471-2105/10/351 © 2009 Via et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Many proteins are highly modular, being assembled from