原创力文档a study of the diagnostic accuracy of the phq-9 in primary care elderly研究的诊断准确性phq - 9在初级护理老人.pdfVIP
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a study of the diagnostic accuracy of the phq-9 in primary care elderly研究的诊断准确性phq - 9在初级护理老人
Phelan et al. BMC Family Practice 2010, 11:63
/1471-2296/11/63
RESEARCH ARTICLE Open Access
A study of the diagnostic accuracy of the PHQ-9
in primary care elderly
1,2* 2 1 3 3 2,4
Elizabeth Phelan , Barbara Williams , Kathryn Meeker , Katie Bonn , John Frederick , James LoGerfo ,
Mark Snowden3
Abstract
Background: The diagnostic accuracy of the Patient Health Questionnaire-9 (PHQ-9) for assessment of depression
in elderly persons in primary care settings in the United States has not been previously addressed. Thus, the
purpose of this study was to evaluate the test performance of the PHQ-9 for detecting major and minor
depression in elderly patients in primary care.
Methods: A prospective study of diagnostic accuracy was conducted in two primary care, university-based clinics
in the Pacific Northwest of the United States. Seventy-one patients aged 65 years or older participated; all
completed the PHQ-9 and the 15-item Geriatric Depression Scale (GDS) and underwent the Structured Clinical
Interview for Depression (SCID). Sensitivity, specificity, area under the receiver operating characteristic (ROC) curve,
and likelihood ratios (LRs) were calculated for the PHQ-9, the PHQ-2, and the 15-item GDS for major depression
alone and the combination of major plus minor depression.
Results: Two thirds of participants were female, with a mean age of 78 and two chronic health conditions. Twelve
percent met SCID criteria for major depression and 13% minor depression. The PHQ-9 had an area under the curve
(AUC) of 0.87 (95% confidence interval [CI], 0.74-1.00) for major depression, while the PHQ-2 and the 15-item GDS
each had an AUC of 0.81 (95% CI for PHQ-2, 0.64-0.98, and for 15-item G
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