原创力文档a unified framework for finding differentially expressed genes from microarray experiments一个统一的框架中寻找差异表达基因微阵列实验.pdfVIP
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a unified framework for finding differentially expressed genes from microarray experiments一个统一的框架中寻找差异表达基因微阵列实验
BMC Bioinformatics BioMed Central
Research article Open Access
A unified framework for finding differentially expressed genes from
microarray experiments
1 1,2,3,4,5
Jahangheer S Shaik and Mohammed Yeasin*
Address: 1Department of Electrical and Computer Engineering, CVPIA Lab, University of Memphis, Memphis, TN-38152, USA, 2Bioinformatics
Program, CVPIA Lab, University of Memphis, Memphis, TN-38152, USA, 3Biomedical Engineering, CVPIA Lab, University of Memphis, Memphis,
TN-38152, USA, 44Center for Advanced Robotics, CVPIA Lab, University of Memphis, Memphis, TN-38152, USA and 5Software Testing and
Excellence Program University of Memphis, Memphis, TN-38152, USA
Email: Jahangheer S Shaik - jshaik@; Mohammed Yeasin* - myeasin@
* Corresponding author
Published: 18 September 2007 Received: 29 March 2007
Accepted: 18 September 2007
BMC Bioinformatics 2007, 8:347 doi:10.1186/1471-2105-8-347
This article is available from: /1471-2105/8/347
© 2007 Shaik and Yeasin; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: This paper presents a unified framework for finding differentially expressed genes (DEGs) from the
microarray data. The proposed framework has three interrelated modules: (i) gene ranking, ii) significance analysis of
gene
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