aberrant stalk development and breakdown of tip dominance in dictyostelium cell lines with rnai-silenced expression of calcineurin b异常茎的开发和故障提示在盘基网柄菌与rnai-silenced细胞系的表达钙调磷酸酶b.pdfVIP
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aberrant stalk development and breakdown of tip dominance in dictyostelium cell lines with rnai-silenced expression of calcineurin b异常茎的开发和故障提示在盘基网柄菌与rnai-silenced细胞系的表达钙调磷酸酶b
BMC Developmental Biology BioMed Central
Research article Open Access
Aberrant stalk development and breakdown of tip dominance in
Dictyostelium cell lines with RNAi-silenced expression of calcineurin
B
1,2 1 1
Katrina Boeckeler , Gilbert Tischendorf , Rupert Mutzel and
Barbara Weissenmayer*1
Address: 1Institut für Biologie – Mikrobiologie, Fachbereich Biologie, Chemie, Pharmazie, Freie Universität Berlin, Königin-Luise-Strasse 12-16,
14195 Berlin, Germany and 2University College London, Department of Biology, Gower Street, London, Wc1 E6BT, UK
Email: Katrina Boeckeler - kboeckeler@web.de; Gilbert Tischendorf - tischend@zedat.fu-berlin.de; Rupert Mutzel - rmutzel@zedat.fu-berlin.de;
Barbara Weissenmayer* - bweiss@zedat.fu-berlin.de
* Corresponding author
Published: 02 March 2006 Received: 28 October 2005
Accepted: 02 March 2006
BMC Developmental Biology2006, 6:12 doi:10.1186/1471-213X-6-12
This article is available from: /1471-213X/6/12
© 2006Boeckeler et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, plays important
roles in various cellular processes in lower and higher eukaryotes. Here we analyze the role of
calcineu
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