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aberrant stalk development and breakdown of tip dominance in dictyostelium cell lines with rnai-silenced expression of calcineurin b异常茎的开发和故障提示在盘基网柄菌与rnai-silenced细胞系的表达钙调磷酸酶b.pdfVIP

aberrant stalk development and breakdown of tip dominance in dictyostelium cell lines with rnai-silenced expression of calcineurin b异常茎的开发和故障提示在盘基网柄菌与rnai-silenced细胞系的表达钙调磷酸酶b.pdf

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aberrant stalk development and breakdown of tip dominance in dictyostelium cell lines with rnai-silenced expression of calcineurin b异常茎的开发和故障提示在盘基网柄菌与rnai-silenced细胞系的表达钙调磷酸酶b

BMC Developmental Biology BioMed Central Research article Open Access Aberrant stalk development and breakdown of tip dominance in Dictyostelium cell lines with RNAi-silenced expression of calcineurin B 1,2 1 1 Katrina Boeckeler , Gilbert Tischendorf , Rupert Mutzel and Barbara Weissenmayer*1 Address: 1Institut für Biologie – Mikrobiologie, Fachbereich Biologie, Chemie, Pharmazie, Freie Universität Berlin, Königin-Luise-Strasse 12-16, 14195 Berlin, Germany and 2University College London, Department of Biology, Gower Street, London, Wc1 E6BT, UK Email: Katrina Boeckeler - kboeckeler@web.de; Gilbert Tischendorf - tischend@zedat.fu-berlin.de; Rupert Mutzel - rmutzel@zedat.fu-berlin.de; Barbara Weissenmayer* - bweiss@zedat.fu-berlin.de * Corresponding author Published: 02 March 2006 Received: 28 October 2005 Accepted: 02 March 2006 BMC Developmental Biology2006, 6:12 doi:10.1186/1471-213X-6-12 This article is available from: /1471-213X/6/12 © 2006Boeckeler et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Calcineurin, the Ca2+/calmodulin-dependent protein phosphatase, plays important roles in various cellular processes in lower and higher eukaryotes. Here we analyze the role of calcineu

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