ac133+ progenitor cells as gene delivery vehicle and cellular probe in subcutaneous tumor models a preliminary studyac133 +祖细胞作为基因运载工具和细胞探针在皮下肿瘤模型初步研究.pdfVIP

BMC Biotechnology BioMed Central Research article Open Access AC133+ progenitor cells as gene delivery vehicle and cellular probe in subcutaneous tumor models: a preliminary study 1,2 1 1 3 1 Ali M Rad , ASM Iskander , Branislava Janic , Robert A Knight , Ali S Arbab and Hamid Soltanian-Zadeh*1,4 Address: 1Department of Radiology, Henry Ford Hospital, Detroit, Michigan, USA, 2Department of Radiology, Massachusetts General Hospital/ Harvard Medical School, Boston, MA, USA, 3Department of Neurology, Henry Ford Hospital, Detroit, Michigan, USA and 4Control and Intelligent Processing Center of Excellence, Department of Electrical and Computer Engineering, University of Tehran, Tehran, Iran Email: Ali M Rad - alirad@; ASM Iskander - aiskander@; Branislava Janic - bjanic@; Robert A Knight - RKNIGHT1@; Ali S Arbab - saali@; Hamid Soltanian-Zadeh* - hamids@ * Corresponding author Published: 27 March 2009 Received: 22 August 2008 Accepted: 27 March 2009 BMC Biotechnology 2009, 9:28 doi:10.1186/1472-6750-9-28 This article is available from: /1472-6750/9/28 © 2009 Rad et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Despite enormous progress in gene therapy for breast cancer, a