achievement of recommended glucose and blood pressure targets in patients with type 2 diabetes and hypertension in clinical practice – study rationale and protocol of dialogue成就推荐的血糖和血压目标2型糖尿病和高血压患者在临床实践中,研究原理和协议的对话.pdfVIP
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achievement of recommended glucose and blood pressure targets in patients with type 2 diabetes and hypertension in clinical practice – study rationale and protocol of dialogue成就推荐的血糖和血压目标2型糖尿病和高血压患者在临床实践中,研究原理和协议的对话
Gitt et al. Cardiovascular Diabetology 2012, 11:148 CARDIO
/content/11/1/148 VASCULAR
DIABETOLOGY
STUDY PROTOCOL Open Access
Achievement of recommended glucose and
blood pressure targets in patients with type 2
diabetes and hypertension in clinical practice –
study rationale and protocol of DIALOGUE
1,2* 3 4 5 1
Anselm K Gitt , Roland E Schmieder , Eva Duetting , Peter Bramlage , Steffen Schneider and
Diethelm Tschöpe6,7 DIALOGUE Study Group*
Abstract
Background: Patients with type 2 diabetes have 2–4 times greater risk for cardiovascular morbidity and mortality
than those without, and this is even further aggravated if they also suffer from hypertension. Unfortunately, less
than one third of hypertensive diabetic patients meet blood pressure targets, and more than half fail to achieve
target HbA1c values. Thus, appropriate blood pressure and glucose control are of utmost importance. Since
treatment sometimes fails in clinical practice while clinical trials generally suggest good efficacy, data from daily
clinical practice, especially with regard to the use of newly developed anti-diabetic and anti-hypertensive
compounds in unselected patient populations, are essential. The DIALOGUE registry aims to close this important
gap by evaluating different treatment approaches in hypertensive type 2 diabetic patients with respect to their
effectiveness and tolerability and their impact on outcomes. In addition, DIALOGUE is the first
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