原创力文档affymapsdetector a software tool to characterize affymetrix genechip？ expression arrays with respect to snpsaffymapsdetector软件工具来描述affymetrix genechip 表达阵列对snp.pdfVIP
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affymapsdetector a software tool to characterize affymetrix genechip？ expression arrays with respect to snpsaffymapsdetector软件工具来描述affymetrix genechip 表达阵列对snp
BMC Bioinformatics BioMed Central
Software Open Access
AffyMAPSDetector: a software tool to characterize Affymetrix
GeneChip™ expression arrays with respect to SNPs
1 2 3
Sunita Kumari , Lalit K Verma and Jennifer W Weller*
Address: 1Department of Computer and Information Science, Indiana University Purdue University Indianapolis, Indianapolis, IN, 46202, USA,
2Eli Lilly and Company, Indianapolis, IN, 46285, USA and 3Computer Science/Bioinformatics program, University of North Carolina at Charlotte,
Charlotte, NC, 28223, USA
Email: Sunita Kumari - skumari@; Lalit K Verma - lalit.verma@; Jennifer W Weller* - jweller2@
* Corresponding author
Published: 30 July 2007 Received: 24 January 2007
Accepted: 30 July 2007
BMC Bioinformatics 2007, 8:276 doi:10.1186/1471-2105-8-276
This article is available from: /1471-2105/8/276
© 2007 Kumari et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Affymetrix gene expression arrays incorporate paired perfect match (PM) and mismatch
(MM) probes to distinguish true signals from those arising from cross-hybridization events. A MM signal
often shows greater intensity than a PM signal; we propose that one underlying cause is the presence of
allelic variant
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