原创力文档an adult patient with henoch-sch？nlein purpura and non-occlusive mesenteric ischemia负责的一个成年病人患有henoch-sch nlein紫癜和non-occlusive肠系膜缺血.pdfVIP
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an adult patient with henoch-sch？nlein purpura and non-occlusive mesenteric ischemia负责的一个成年病人患有henoch-sch nlein紫癜和non-occlusive肠系膜缺血
Oshikata et al. BMC Research Notes 2013, 6:26
/1756-0500/6/26
CASE REPORT Open Access
An adult patient with Henoch-Schönlein purpura
and non-occlusive mesenteric ischemia
1 1* 2 2 3
Chiyako Oshikata , Naomi Tsurikisawa , Masakazu Takigawa , Tomoko Omori , Satoshi Sugano ,
1 4 5 1
Takahiro Tsuburai , Hiroyuki Mitomi , Tamiko Takemura and Kazuo Akiyama
Abstract
Background: Onset of Henoch-Schönlein purpura (HSP) in middle age is uncommon, and adults with renal or
gastrointestinal involvement present with more severe disease than do similar pediatric patients.
Case presentation: We present the case of a 69-year-old male with HSP who, after treatment with steroids,
cyclophosphamide, and continuous intravenous prostaglandin E1 (PGE1), died as a result of severe gastrointestinal
involvement with non-occlusive mesenteric ischemia (NOMI). Vascular narrowing associated with the NOMI
improved after catheter injection of PGE1 and prednisolone, but the patient died of bleeding from an exposed
small vessel. At autopsy there was no active vasculitis in the jejunal submucosa.
Conclusion: Treatment with PGE1 and prednisolone might improve small-vessel vasculitis associated with NOMI.
Keywords: Henoch-Schönlein purpura, Intervention, Non-occlusive mesenteric ischemia, Small vessel vasculitis
Background Risk factors for NOMI include hypovolemia, hypotension,
Henoch-Schönlein purpura (HSP) is characterized by a low cardiac output status, renal or hepatic disease, cardiac
leukocytoclastic vasculitis involving the
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