an analytic and systematic framework for estimating metabolic flux ratios from 13c tracer experiments估计代谢通量分析和系统框架比率从13 c示踪实验.pdfVIP
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an analytic and systematic framework for estimating metabolic flux ratios from 13c tracer experiments估计代谢通量分析和系统框架比率从13 c示踪实验
BMC Bioinformatics BioMed Central
Methodology article Open Access
An analytic and systematic framework for estimating metabolic flux
ratios from 13C tracer experiments
1,2 1 3 2
Ari Rantanen* , Juho Rousu , Paula Jouhten , Nicola Zamboni ,
3 1
Hannu Maaheimo and Esko Ukkonen
Address: 1Department of Computer Science, University of Helsinki, Finland, 2Institute of Molecular Systems Biology, ETH Zurich, Switzerland and
3VTT Technical Research Centre of Finland, Finland
Email: Ari Rantanen* - ari.rantanen@iki.fi; Juho Rousu - juho.rousu@cs.helsinki.fi; Paula Jouhten - pjouhten@mappi.helsinki.fi;
Nicola Zamboni - zamboni@imsb.biol.ethz.ch; Hannu Maaheimo - hannu.maaheimo@helsinki.fi; Esko Ukkonen - ukkonen@cs.helsinki.fi
* Corresponding author
Published: 6 June 2008 Received: 14 January 2008
Accepted: 6 June 2008
BMC Bioinformatics 2008, 9:266 doi:10.1186/1471-2105-9-266
This article is available from: /1471-2105/9/266
© 2008 Rantanen et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Metabolic fluxes provide invaluable insight on the integrated response of a cell to
environmental stimuli
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