an ancient spliceosomal intron in the ribosomal protein l7a gene (rpl7a) of giardia lamblia一个古老spliceosomal在核糖体蛋白基因内区l7a兰伯氏贾第虫的基因(rpl7a).pdfVIP
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an ancient spliceosomal intron in the ribosomal protein l7a gene (rpl7a) of giardia lamblia一个古老spliceosomal在核糖体蛋白基因内区l7a兰伯氏贾第虫的基因(rpl7a)
BMC Evolutionary Biology BioMed Central
Research article Open Access
An ancient spliceosomal intron in the ribosomal protein L7a gene
(Rpl7a) of Giardia lamblia
† †
Anthony G Russell , Timothy E Shutt , Russell F Watkins and
Michael W Gray*
Address: Program in Evolutionary Biology, Canadian Institute for Advanced Research, Department of Biochemistry and Molecular Biology,
Dalhousie University, Halifax, Nova Scotia B3H 1X5, Canada
Email: Anthony G Russell - russella@dal.ca; Timothy E Shutt - tshutt@dal.ca; Russell F Watkins - rwatkins@dal.ca;
Michael W Gray* - m.w.gray@dal.ca
* Corresponding author †Equal contributors
Published: 18 August 2005 Received: 22 April 2005
Accepted: 18 August 2005
BMC Evolutionary Biology 2005, 5:45 doi:10.1186/1471-2148-5-45
This article is available from: /1471-2148/5/45
© 2005 Russell et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: Only one spliceosomal-type intron has previously been identified in the unicellular
eukaryotic parasite, Giardia lamblia (a diplomonad). This intron is only 35 nucleotides in length and
is unusual in possessing a non-canonical 5 intron boundary sequence, CT, instead of GT.
Results: We have identified a second spliceosomal
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