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an svm-based system for predicting protein subnuclear localizations基于系统预测蛋白质的亚核的本地化
BMC Bioinformatics BioMed Central
Methodology article Open Access
An SVM-based system for predicting protein subnuclear
localizations
Zhengdeng Lei and Yang Dai*
Address: Department of Bioengineering (MC063), University of Illinois at Chicago, 851 South Morgan Street, Chicago IL 60607, USA
Email: Zhengdeng Lei - zlei2@; Yang Dai* - yangdai@
* Corresponding author
Published: 07 December 2005 Received: 09 May 2005
Accepted: 07 December 2005
BMC Bioinformatics 2005, 6:291 doi:10.1186/1471-2105-6-291
This article is available from: /1471-2105/6/291
© 2005 Lei and Dai; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The large gap between the number of protein sequences in databases and the
number of functionally characterized proteins calls for the development of a fast computational tool
for the prediction of subnuclear and subcellular localizations generally applicable to protein
sequences. The information on localization may reveal the molecular function of novel proteins, in
addition to providing insight on the biological pathways in which they function. The bulk of past
work has been focused on protein subcellular localizations. Furthermore, no specific tool has been
dedic
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