application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote homolog detection非负矩阵分解的应用改善褶皱profile-profile对齐特征识别和远程同族体检测.pdfVIP

下载本文档

7
0
约7.33万字
约 11页
2017-09-11 发布于上海
举报
版权申诉

application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote homolog detection非负矩阵分解的应用改善褶皱profile-profile对齐特征识别和远程同族体检测.pdf

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote homolog detection非负矩阵分解的应用改善褶皱profile-profile对齐特征识别和远程同族体检测

BMC Bioinformatics BioMed Central Research article Open Access Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote homolog detection 1 1 1 1,2 Inkyung Jung , Jaehyung Lee , Soo-Young Lee and Dongsup Kim* Address: 1Department of Bio and Brain Engineering, KAIST, Daejeon, 305-701, South Korea and 2KAIST Institute for the BioCentury, KAIST, Daejeon, 305-701, South Korea Email: Inkyung Jung - snowdrop83@; Jaehyung Lee - jaehyung.lee@kaist.ac.kr; Soo-Young Lee - sylee@kaist.ac.kr; Dongsup Kim* - kds@kaist.ac.kr * Corresponding author Published: 1 July 2008 Received: 8 January 2008 Accepted: 1 July 2008 BMC Bioinformatics 2008, 9:298 doi:10.1186/1471-2105-9-298 This article is available from: /1471-2105/9/298 © 2008 Jung et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This unique ability makes NMF a potentially promising method for biological sequence analysis. Here, we apply NMF to fold recognition and remote homolog d