hodgkins lymphoma presenting with markedly elevated ige a case report霍奇金淋巴瘤有明显升高ige案例报告.pdfVIP

Allergy, Asthma Clinical Immunology BioMed Central Case report Open Access Hodgkins lymphoma presenting with markedly elevated IgE: a case report Anne K Ellis 1,2 and Susan Waserman* 1 Address: 1Division of Clinical Immunology Allergy, Department of Medicine, McMaster University, Hamilton, ON, Canada and 2Division of Allergy Immunology, Department of Medicine, Queens University, Kingston, ON, Canada Email: Anne K Ellis - ellis.anne@; Susan Waserman* - waserman@mcmaster.ca * Corresponding author Published: 7 December 2009 Received: 27 October 2009 Accepted: 7 December 2009 Allergy, Asthma Clinical Immunology 2009, 5:12 doi:10.1186/1710-1492-5-12 This article is available from: /content/5/1/12 © 2009 Ellis and Waserman; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Markedly elevated IgE as a manifestation of a lymphoproliferative disorder has been only rarely reported. Case Presentation: We present the case of a 22 year old female referred to the adult Allergy Clinical Immunology clinic for an extremely elevated IgE level, eventually diagnosed with Hodgkins lymphoma. She had no history of atopy, recurrent infections, eczema or periodontal disease; stool was negative for ova parasites. Chest X-ray revealed large bilater