organic isfet based on poly (3-hexylthiophene)基于聚有机isfet(3-hexylthiophene).pdf

Sensors 2010, 10, 2262-2273; doi:10.3390/s100302262 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Article Organic ISFET Based on Poly (3-hexylthiophene) Giuseppe Scarpa 1,*, Anna-Lena Idzko 2, Anandi Yadav 1 and Stefan Thalhammer 2,* 1 Institute for Nanoelectronics, Technische Universität München, Arcisstrasse 21, D-80333 Munich, Germany; E-Mail: anandi.yadav@mytum.de 2 Helmholtz Zentrum München, German Research Center for Environmental Health, Institute of Radiation Protection, Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany; E-Mail: anna-lena.idzko@helmholtz-muenchen.de * Authors to whom correspondence should be addressed; E-Mails: scarpa@tum.de (G.S.); stefan.thalhammer@helmholtz-muenchen.de (S.T.); Tel.: +49-89-289-25334; Fax: +49-89-289-25337; Tel.: +49-89-3187-2893; Fax: +49-89-3187-3323 (S.T.). Received: 24 January 2010; in revised form: 13 February 2010 / Accepted: 10 March 2010 / Published: 19 March 2010 Abstract: We have fabricated organic field-effect transistors (OFETs) with regioregular poly(3-hexylthiophene) (P3HT) operable at low-voltages in liquid solutions, suitable for in vitro biosensing applications. Measurements in electrolytes have shown that the performance of the transistors did not deteriorate and they can be directly used as ion- sensitive transducers. Furthermore, more complex media have been tested, with the perspective of cell analysis. Degradation effects acting on the