optoelectronic capillary sensors in microfluidic and point-of-care instrumentation光电毛细管传感器在微流控和医疗点仪器.pdf

Sensors 2010, 10, 3771-3797; doi:10.3390/s100403771 OPEN ACCESS sensors ISSN 1424-8220 /journal/sensors Review Optoelectronic Capillary Sensors in Microfluidic and Point-of-Care Instrumentation Michał Borecki 1,*, Michael L. Korwin-Pawlowski 2, Maria Beblowska 1, Jan Szmidt 1 and 1 Andrzej Jakubowski 1 Institute of Microelectronics and Optoelectronics, Warsaw University of Technology, Koszykowa 75, 00-662 Warsaw, Poland; E-Mails: beblowska@.pl (M.B.); j.szmidt@.pl (J.S.); a.jakubowski@.pl (A.J.) 2 Département d’informatique et d’ingénierie, Université du Québec en Outaouais, 101 rue Saint-Jean-Bosco, Gatineau, QC J8X 3X7, Canada; E-Mail: michael.korwin-pawlowski@uqo.ca * Author to whom correspondence should be addressed; E-Mail: borecki@.pl; Tel.: +48-22-234-7749; Fax: +48-22-628-8740. Received: 15 February 2010; in revised form: 10 March 2010 / Accepted: 30 March 2010 / Published: 14 April 2010 Abstract: This paper presents a review, based on the published literature and on the authors’ own research, of the current state of the art of fiber-optic capillary sensors and related instrumentation as well as their applications, with special emphasis on point-of-care chemical and biochemical sensors, systematizing the various types of sensors from the point of view of the principles of their construction and operation. Unlike classical fiber-optic sensors which rely on changes in light propagation inside the fiber as affected by outside