outdoor particulate matter and childhood asthma admissions in athens, greece a time-series study室外颗粒物和儿童哮喘招生在雅典,希腊一个时间序列的研究.pdfVIP

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outdoor particulate matter and childhood asthma admissions in athens, greece a time-series study室外颗粒物和儿童哮喘招生在雅典,希腊一个时间序列的研究.pdf

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outdoor particulate matter and childhood asthma admissions in athens, greece a time-series study室外颗粒物和儿童哮喘招生在雅典,希腊一个时间序列的研究

Nastos et al. Environmental Health 2010, 9:45 /content/9/1/45 RESEARCH Open Access Outdoor particulate matter and childhood asthma admissions in Athens, Greece: a time-series study 1* 2 3 4 5 Panagiotis T Nastos , Athanasios G Paliatsos , Michael B Anthracopoulos , Eleftheria S Roma , Kostas N Priftis Abstract Background: Particulate matter with diameter less than 10 micrometers (PM10) that originates from anthropogenic activities and natural sources may settle in the bronchi and cause adverse effects possibly via oxidative stress in susceptible individuals, such as asthmatic children. This study aimed to investigate the effect of outdoor PM10 concentrations on childhood asthma admissions (CAA) in Athens, Greece. Methods: Daily counts of CAA from the three Children’s Hospitals within the greater Athens’ area were obtained from the hospital records during a four-year period (2001-2004, n = 3602 children). Mean daily PM10 concentrations recorded by the air pollution-monitoring network of the greater Athens area were also collected. The relationship between CAA and PM10 concentrations was investigated using the Generalized Linear Models with Poisson distribution and logistic analysis. Results: There was a statistically significant (95% CL) relationship between CAA and mean daily PM 10 concentrations on the day of exposure (+3.8% for 10 μg/m3 increase in PM10 concentrations), while a 1-day lag (+3.4% for 10 μg/m3 increase in PM10 concentrations) and a 4-day lag (+4.3% for 10 μg/m3 increase in PM10 concentrations) were observed for older asthmatic children (5-14 year-old). High mean daily PM10 concentration (the highest 10%; 65.69 μg/m3) doubled the risk of asthma exacerbatio