oxygen uptake-to-delivery relationship a way to assess adequate flow氧气uptake-to-delivery关系评估充分流动的一种方式.pdfVIP

Available online /content/10/S3/S4 Review Oxygen uptake-to-delivery relationship: a way to assess adequate flow Vincent Caille1 and Pierre Squara2 1Service de Chirurgie Cardio-vasculaire, Hôpital Foch, Suresnes, France 2Ceric, Clinique Ambroise Pare, Neuilly-Sur-Seine, France Corresponding author: Pierre Squara, pierre.squara@wanadoo.fr Published: 27 November 2006 Critical Care 2006, 10(Suppl 3):S4 (doi:10.1186/cc4831) This article is online at /content/10/S3/S4 © 2006 BioMed Central Ltd Abstract A reasonable assumption is that below a critical level the Invasive and noninvasive monitoring facilitates clinical evaluation oxygen consumption (VO2) is inversely related to the risk for when resuscitating patients with complex haemodynamic disorders. cell dysfunction and necrosis and to the severity of shock. If the macrocirculation is to be stable, then it must adapt to blood Among the various haemodynamic variables that may be flow or blood flow must be optimized. The objective of flow evaluated, a VO2 below the required level is most strongly monitoring is to assist with matching observed oxygen consump- related to death [2]. Once a substantial amount of cell tion (VO2) to pathophysiological needs. If an adequate balance necrosis has occurred, organ function recovery is not always cannot be maintained then dysoxia occurs. In this review we propose a simple schema for global reasoning; we discuss the